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Fueling Active Lifestylers with Probiotics

Active consumers want natural solutions to enjoy healthy aging. They can accomplish this with a unique trio of strains, shown to enhance fitness goals and improve recovery.

How do you neatly pull together healthy aging and active nutrition? By nourishing the microbiome to strengthen the gut-muscle axis. How is this accomplished? Through a unique probiotic blend clinically studied to show improvements in exercise performance and recovery by working on the gut-muscle axis (G-MA).

About the G-MA

The gut-muscle axis, a newer pathway involving the microbiome, primarily regulates muscle proteins and function. 1

The gut-muscle axis reveals itself through an active lifestyle. Intense and frequent workouts generate chronic oxidative stress and inflammation that affects how muscles adapt to workouts but also disturbs intestinal homeostasis, including the microbiota profile. Researchers state that optimal intestinal microbiota composition can reduce amounts of inflammatory markers as well as impede reactive oxygen species production. In this study, the researchers recommend supplementation with probiotics to enhance the gut-muscle axis; and they emphasize this for all, not only for athletes. 2

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How a New Probiotic Ingredient Works

A study on a novel probiotic blend of three lyophilized strains from ADM has shown its ability to support the enhancement of exercise/fitness and improve recovery for active consumers by influencing the gut-muscle axis via the microbiome.

The randomized double-blind, controlled clinical trial evaluated the effects of consuming the probiotic blend (Bifidobacterium longum CECT 7347, Lactobacillus casei CECT 9104, and Lactobacillus rhamnosus CECT 8361). In the study, 43 male cyclists supplemented with the probiotic or placebo daily for six weeks.

The study team examined biochemical markers of excessive oxidation such as isoprostane (formed from free radical catalyzed peroxidation of EFAs), serum malondialdehyde (MDA, a marker of oxidative stress) oxidized low-density lipoprotein (Ox-LDL, or elevated bad cholesterol), 8-hydroxy-2'-deoxiguanosine (8-OHdG, a biomarker of oxidative DNA damage), and protein carbonyl (oxidative damage in proteins), as well as the antioxidant enzymes glutathione peroxidase (GPx), and superoxide dismutase (SOD). The objective was to compare how the probiotic blend favorably impacted levels of these biomarkers against placebo and to quantify those levels.

The researchers analyzed the data and found that supplementing with the proprietary strain trio reduces post-exercise-related oxidative stress, which supports aspects of exercise and recovery. It reduces serum oxidized low-density lipoprotein and elevated serum superoxide dismutase levels, providing a favorable balance for regular sustained activity. Supporting an active lifestyle is the first step toward healthy aging and ADM’s new probiotic blend provides formulation flexibility to bring function and convenience.

“Having new and exciting solutions within the active lifestyle and healthy aging categories is extremely exciting as there have been very few proven ingredients released in this space in recent years,” said Vaughn DuBow, Global Director of Marketing, Microbiome for ADM. “Additionally, with the rise of popularity in probiotics over the past several years, this formula enables dietary supplement companies the opportunity to provide consumers with the health benefits they’re looking for most, in a new, unique, and differentiated offering.”

DuBow adds that ADM is “constantly working on additional clinical studies to explore more possibilities within the microbiome space, and expects to find far more benefits available from this blend thanks to the powerful gut muscle axis connection.”

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Probiotics Scale New Consumer Heights

This study exemplifies the increased research of the microbiome. For example, in 2021 alone, there were just under 10,000 published studies examining this in vivo environment -- what impacts it, and how nutrition such as probiotic strains encourage it to influence health. Further, products that cater to the microbiome reached $6.97 billion in sales in 2021, a figure that is expected to blossom to $9.32 billion in 2026.

This accelerated research may likely be both a cause and effect of the consumer clamor for probiotics: in the 2019 Kerry Global Consumer Survey “Digestive & Immune Health,” 58% of global consumers understand the benefits of beneficial bacteria residing in their GI tract and 71% of users believe probiotics can support an active lifestyle. Further, the report noted that in the top three perceived benefits of probiotics, 71% of consumers believe they support healthy aging.

Probiotics are well understood to be beneficial for health, yet consumers are just gaining an understanding of the microbiome, at least in general.  According to FMCG Gurus’ March 2022 report, “Health and Wellness: Gut Microbiome in 2022,” while 67% of global consumers said they were aware about bacteria that exist in their GI systems, only15% have heard of the gut microbiome. The same report showed that globally, 43% of consumers have used probiotics in the previous 12 months.

Like the strains harmoniously blending in ADM’s new probiotic to provide benefits for routine fitness, this market data coalesces to strongly suggest there are numerous formulation opportunities with probiotics, especially unique probiotic blends that support active lifestyles.

The active nutrition category has expanded beyond elite athletes and includes adults of all ages. There is rising consumer interest in how probiotics can benefit their overall health and support their active lifestyle goals to generate a higher sense of sustained well-being.

ADM’s new proprietary probiotic blend is non-GMO, Halal, Kosher, and free of gluten and lactose. It is also QPS-list compliant. It can swiftly become the “go to” probiotic for health-and-wellness consumers dedicated to remaining active, strong, flexible and ready to go!

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References

1 Franzoni, Oxidaitve Medicine and Cellular Longevity 2022 (October)

2 Przewlocka, et al. Nutrients 2020 12(5):1451

3 Sanchez Macarro, Antioxidants (Basel) 2021 Feb 22;10(2):323

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