In a pilot study twenty patients were switched over from non-steroidal anti-inflammatory drug (NSAID's) therapies to the Boswellia Serrata Extract (BSE) of Salki Guggul (Cap Wokvel, manufactured by Pharmanza India) containing 333 mg of BSE per capsule, in the dose of one capsule three times a day, for the total duration of 45 days. After the study period, all patients reported decrease in knee pain, increased knee flexion, increased walking distance, improvement in capacity of climbing stairs, better ability in kneeling, crossed legged sitting and squatting. The knee range of movement was improved. The frequency of swelling in the knee joint was decreased. Encouraged by the positive results of the pilot study, Geni Inc sponsored the double blind randomized cross over study. The study is underway with results expected in February 2002. GENI Inc, supplies the natural products industry with the finest quality Ayurvedic herbal extracts, Standardized extracts, Mineral yeasts, GMO- free Soy Products, Nutraceuticals, and Kosher certified products.